MenaquinGold® – Natural Vitamin K2-7 for Bones

Bones play many important roles in the body from providing structure, protecting organs, anchoring muscles, as well as storing minerals. But did you know? People commonly reach their peak bone mass around age 30. Then, bone mass and density will gradually decrease as we age, which may lead to weakness of bone and eventually osteoporosis. Osteoporosis is a disease in which the bones become weak and fragile. It is also known as porous bones with increased fracture risk and therefore, bones are more likely to break.

If we are able to build strong and healthy bones during childhood and adolescence, the less likely we are to develop osteoporosis as we age. But don’t worry because we can take steps during adulthood to protect bone health too. How can we maintain our bone health? Many people don’t understand that it is not enough to maintain bone health with calcium or vitamin D intake only. We also need Vitamin K2, which plays a central role in calcium metabolism and helps to build and maintain bone mineral density.

Study conducted in healthy prepubertal children observed that the consumption of Vitamin K2-7 reduced the concentration of inactive undercarboxylated osteocalcin (ucOC) and increased the concentration of carboxylated osteocalcin (cOC), thereby, indicate the increase of Vitamin K status in healthy prepubertal children. Osteocalcin (OC) is a marker of osteoblasts, the cells that form new bones, and therefore reflects the rate of bone formation which related to bone health[1]. This means Vitamin K2-7 consumption in children could help to improve bone mass since early age.

An epidemiology population-based study was also conducted to Eastern Japanese women, Western Japanese women, and British women. The study result showed that Vitamin K2-7 serum levels were highest in Eastern Japanese women and lowest in British women. Natto, which known as one of the sources of vitamin K2, is believed to be the major contributor to the higher serum Vitamin K2-7 concentration in Eastern Japanese since it is consumed more frequently in Eastern Japan compared to Western Japan and not at all a food item in Britain. This study also observed that hip fracture rates were lowest in Eastern Japanese women and highest in British women. Similarly, this happened because highest level of natto consumption in East Japan, which resulted in higher Vitamin K2-7 concentration, higher bone mass and therefore they had lower hip fracture rates[2].

MenaquinGold® is a natural Vitamin K2-7 known as menaquinone-7 (MK-7, vitamin K2-7) from fermentation by Bacillus Natto. It is proven to be effective in helping to improve bone mass and keep cardiovascular health with just a little dosage of 45 µg/day.

Source:

  1. Summeren, M.J.H., L.A.J.L.M. Braam, M.R. Lilien, L.J. Schurgers, W. Kuis and C. Vermeer. 2009. “The effect of menaquinone-7 (vitamin K2) supplementation on osteocalcin carboxylation in healthy prepubertal children”. British Journal of Nutrition: 1-8.
  2. Kaneki, M., S.J. Hedges, T. Hosoi, S. Fujiwara, MD, A. Lyons, S.J. Crean, N. Ishida, M. Nakagawa, M. Takechi, Y. Sano, Y. Mizuno, S. Hoshino, M. Miyao, S. Inoue, K. Horiki, M. Shiraki, Y. Ouchi, and H. Orimo. 2001. “Japanese Fermented Soybean Food as the Major Determinant of the Large Geographic Difference in Circulating Levels of Vitamin K2: Possible Implications for Hip-Fracture Risk”. Nutrition Vol. 17 No. 4: 315-321.

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